https://ashwingopinath.com/home daily 1.0 2020-10-05 https://ashwingopinath.com/large-area-nanopatterning daily 0.75 2017-12-02 https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1512193814166-P5XMIX57EMXY4SNL8SZL/LargeAreaNanoTexturing_v1.png Large area metasurfaces Origami Metasurfaces : (a) Three approaches (1-3) to organize DNA origami periodic, crystalline or random pattern; (4-8) are different potential methods to create light scatterers using DNA origami. (b) An optical meta-surface created by metal nanoparticle clusters [] ; (c) electrically tunable optical meta-surfaces created by graphene nanodisks [] (scale bar, 1um); (d) lithographically fabricated surface that mimics the structural color properties of a blue morpho butterfly [] (scale bar, 1um); (e) schema for growing silica layer on DNA origami https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1512197485650-7VKE5L24J3CPZYQ3UVSF/LargeAreaNanoTexturing_v2.png Large area metasurfaces (Origami Polymer): Two schema for converting an immobilized DNA origami into a geometrically well-defined polymer island that can, in turn, be used as mask for metal liftoff or dry etching. (Top) using ATRP or RAFT initiators on DNA origami or (bottom) using DNA origami to direct the phase separation of polymer blend. https://ashwingopinath.com/dna-origami-one-tool-to-unify-them-all-1 daily 0.75 2022-06-21 https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511122671308-W7XJXPT1R9AURH6UV049/Origami_Toolbox.png DNA origami: One tool to unify them all Origami toolbox: The modules a-e together form the "origami nanofabrication toolbox" that uses DNA origami along top-down nanofabrication techniques to position and orient individual molecules as well as direct the etching and growth of inorganic materials with shape, resolution and ease unmatched by any other technique. https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1510321747241-Z5IVL5CPFUOJRXU5FCMP/Vision.png DNA origami: One tool to unify them all Vision: (Top) The well established micro-fabrication process flow which involves a patterning step and a material processing step;(bottom) Examples of inorganic and organic molecules as well as self-assembled nano-structures that can be organized on the DNA origami. All the green arrows represent well established protocols while the red arrows and boxes represent my ongoing efforts. https://ashwingopinath.com/artificial-synapse daily 0.75 2017-12-02 https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1512192740834-8ZW4JV9MEPL7NRLRQEON/BrainMachineInterface_v1.png Artificial Synapse Synthetic synapse: (a) Schematic showing the fabrication of the “synthetic synapse” starting with an array of transistors on top of which DNA origami are localized, followed by creation of femotoliter chambers, attachment of DNA nanopores and finally plating of the cells; (b) Cross-section view of a single synthatic synapse or ‘pixel’ with a transistor, DNA origami and nanopore interfacing with the cell at a defined distance; (c) is a cartoon of a natural electrical synapse connecting two neurons through bi-directional gap-junction ion channels; (d) is a schematic of DNA nanopore created from a small six helix bundle with a hydrophobic belt created by attached 30 hydrophobic moeities; (e) is a schematic of second approach to cellular interface where an antibody or aptamer is used to recruit a specific natural ion channel undergoing lateral diffusion on the cell surface.   https://ashwingopinath.com/engineering-quantum-light-sources daily 0.75 2018-06-27 https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511758326177-X5DV9XA5ICWFK8LP94P5/SuperradianceOrigami.png Engineering quantum light sources Origami SR: (a) Comparison of hypothetical SR decay from a dense cluster of dipoles in a volume much smaller than λ3 as compared to radiative decay from same number of dipoles distributed sparsely. (b) The collective SR interaction will likely a polarization dependence based on the arrangement of the emitters (similar to phased arrays). (c) the SR signal is going to be modulated based on the number of emitters within a resonator as well their relative position with respect to each other on waveguide. https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511751961098-8YUCBJV36DWHVAVZGNQV/SinglePhotonSuperradianceEngineering_v1.png Engineering quantum light sources Origami SPS: (a) The framework for constructing an array of individual emitters and subsequently constructing waveguide (1), optical resonator (2) or plasmonic resonator (3) around the emitters; (b) Schema of the proposed Hong-ou-mandel experiments with two independantly triggered (and tuned) single photon emitters that interfere at a 50:50 splitter followed by integrated single photon detectors. https://ashwingopinath.com/about-me daily 0.75 2021-02-18 https://ashwingopinath.com/stochasticity-of-biochemical-networks daily 0.75 2017-11-21 https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511232235785-XZQQVY05V8XSJUH5EA9I/BrainMachineInterface_v2.png "Reproducible" stochasticity Stochasticity: The schema (top, left) and composite flourescent and brightfield microscope image (top, right) of the lipid bilayer capped femo- and atto-liter chambers with discrete origami (with single Cy3 molecules) positioned inside each chamber. (Bottom) the cross section of a single chamber showing the lipidbilayer cap along with the DNA origami and associated flouroscent molecule. https://ashwingopinath.com/publications daily 0.75 2019-12-04 https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511998179827-4YM2JYRTLLGBPPOA3NL2/image-asset.jpeg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511998147396-ISH2PHLPZXNSNJDKWP79/image-asset.jpeg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511997894344-P346ZCAKQJ8PT8FMC6AK/AdvancedMaterials_2010.jpg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511998082102-WCK4KQ977W2LMPPEC5K3/NanoLetter_2008.jpg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511998103928-6RIN929KBKWNIOCIQ2WD/OpticsExpress_Svetlana_2008.jpg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1513968812190-U64AJHJK5NGBWU66R9W9/Empty.jpg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511998124196-ADVFGXDYP6UD142U33Q4/AdvancedMaterials_2008.jpg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511997733294-L8PYQ5WIFRCU9DQKIUNG/image-asset.jpeg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511997647516-043UI8VN8YMHFSG6W8M3/Yoda-DarthVader-AbsolutePlacement-2017.jpg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511998164489-ZM4ZYLG8HO86U4V265D6/image-asset.jpeg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511997908409-NUDHF7K13TW7WOL1S6R1/ErEnhancement_2009.jpg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511997956056-JU3VNZT92EFO87K8UA31/image-asset.jpeg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511997987562-3FX7Q525LPFQ7F2CL2EA/image-asset.jpeg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511997702155-8S23A9MJGJ0XU57BA0BJ/StarryNight-Nature-2016.jpg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511998053784-14XV5GL7166QWR1B62TC/Empty.jpg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511998017920-H5N4RY104E61AAOUXSNL/image-asset.jpeg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511997240294-OK7TWFIOCAF3QIR43UFD/Empty.jpg Publications https://images.squarespace-cdn.com/content/v1/524ae58ae4b09e34451f53be/1511997768397-VH4VY9JWW1JJNH3897LM/image-asset.jpeg Publications https://ashwingopinath.com/publiccalendar daily 0.75 2019-01-29 https://ashwingopinath.com/calendar daily 0.75 2021-02-18 https://ashwingopinath.com/team daily 0.75 2021-01-18 https://ashwingopinath.com/chatbot daily 0.75 2023-10-13 https://ashwingopinath.com/hometest daily 0.75 2024-06-04